Invention Grant
US07691405B2 Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
有权
基于脂质纳米颗粒的组合物和递送生物活性分子的方法
- Patent Title: Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
- Patent Title (中): 基于脂质纳米颗粒的组合物和递送生物活性分子的方法
-
Application No.: US12027952Application Date: 2008-02-07
-
Publication No.: US07691405B2Publication Date: 2010-04-06
- Inventor: Tongqian Chen , Kurt Vagle , Chandra Vargeese , Weimin Wang , Ye Zhang
- Applicant: Tongqian Chen , Kurt Vagle , Chandra Vargeese , Weimin Wang , Ye Zhang
- Applicant Address: US CA San Francisco
- Assignee: Sirna Therapeutics, Inc
- Current Assignee: Sirna Therapeutics, Inc
- Current Assignee Address: US CA San Francisco
- Agent Matthew A. Leff; David A. Muthard
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K51/00 ; C07H21/04
Abstract:
The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver short interfering nucleic acid (siNA). The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP).
Public/Granted literature
- US20090048197A1 Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules Public/Granted day:2009-02-19
Information query
