Invention Grant
- Patent Title: Methods and compositions for treating obesity
- Patent Title (中): 用于治疗肥胖症的方法和组合物
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Application No.: US11571714Application Date: 2005-07-07
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Publication No.: US07691578B2Publication Date: 2010-04-06
- Inventor: Bruce M. Spiegelman
- Applicant: Bruce M. Spiegelman
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Foley Hoag, LLP
- International Application: PCT/US2005/024064 WO 20050707
- International Announcement: WO2006/014529 WO 20060209
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/00 ; G01N33/53

Abstract:
The present invention relates to therapeutic compositions for treating or preventing obesity and obesity-related disorders in a subject. The present invention also relates to the use of PGC-1 expression levels to determine the safe dosage range for known or putative respiration uncoupling agents for use as anti-obesity therapeutics. The present invention further relates to methods for identifying new compounds that have respiration uncoupling activity.
Public/Granted literature
- US20080262093A1 Methods and Compositions for Treating Obesity Public/Granted day:2008-10-23
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