Invention Grant
- Patent Title: Methods of secretory vimentin detection and modulation
- Patent Title (中): 分泌波形蛋白检测和调制方法
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Application No.: US10670065Application Date: 2003-09-24
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Publication No.: US07691582B2Publication Date: 2010-04-06
- Inventor: David M. Markovitz , Nirit Mor-Vaknin , Antonello Punturieri
- Applicant: David M. Markovitz , Nirit Mor-Vaknin , Antonello Punturieri
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones S.C.
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present invention relates to methods for screening and modulating the bioavailability of extracellular secretory vimentin. In particular, the present invention provides inhibitors and activators of secretory vimentin including antibodies, small interfering RNAs, and antisense oligonucleotides. The present invention thus provides novel drug targets for enhanced anti-microbial response, and methods of using such modulators to beneficially alter the pathophysiologic effects of secretory vimentin.
Public/Granted literature
- US20040121419A1 Methods of secretory vimentin detection and modulation Public/Granted day:2004-06-24
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