Invention Grant
- Patent Title: Polysialic acid derivatives
- Patent Title (中): 聚唾液酸衍生物
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Application No.: US10568111Application Date: 2004-08-12
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Publication No.: US07691826B2Publication Date: 2010-04-06
- Inventor: Dale Howard Hreczuk-Hirst , Sanjay Jain , Peter Laing , Gregory Gregoriadis , Ioannis Papaioannou
- Applicant: Dale Howard Hreczuk-Hirst , Sanjay Jain , Peter Laing , Gregory Gregoriadis , Ioannis Papaioannou
- Applicant Address: GB London
- Assignee: Lipoxen Technologies Limited
- Current Assignee: Lipoxen Technologies Limited
- Current Assignee Address: GB London
- Agency: Morrison & Foerster LLP
- Priority: EP03254988 20030812; EP03255200 20030821
- International Application: PCT/GB2004/003488 WO 20040812
- International Announcement: WO2005/016973 WO 20050224
- Main IPC: A61K31/7008
- IPC: A61K31/7008 ; A61K31/7012 ; A61K31/7028 ; A61K31/7056 ; A61K31/715
Abstract:
A polysialic acid compound is reacted with a hetero-bifunctional reagent to introduce a pendant functional group for site-specific conjugation to sulfhydryl groups, for instance side chains of cysteine units in drugs, drug delivery systems, proteins or peptides. The functional group is, for instance, an N-maleimide group.
Public/Granted literature
- US20060270830A1 Polysialic acid derivatives Public/Granted day:2006-11-30
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