Invention Grant
- Patent Title: Pyrrole derivatives as antimycobacterial compounds
-
Application No.: US10497615Application Date: 2002-09-20
-
Publication No.: US07691837B2Publication Date: 2010-04-06
- Inventor: Sudershan Kumar Arora , Neelima Sinha , Sanjay Jain , Ram Shankar Upadhayaya , Gourhari Jana , Shankar Ajay , Rakesh Kumar Sinha
- Applicant: Sudershan Kumar Arora , Neelima Sinha , Sanjay Jain , Ram Shankar Upadhayaya , Gourhari Jana , Shankar Ajay , Rakesh Kumar Sinha
- Applicant Address: IN Mumbai
- Assignee: Lupin Limited
- Current Assignee: Lupin Limited
- Current Assignee Address: IN Mumbai
- Agency: Merchant & Gould P.C.
- International Application: PCT/IN02/00189 WO 20020920
- International Announcement: WO2004/026828 WO 20040401
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A01N43/40 ; A61K31/33 ; A61K31/55 ; A61K31/497 ; A61K31/435 ; C07D223/00 ; C07D243/00 ; C07D241/04 ; C07D295/00 ; C07D213/00

Abstract:
Novel pyrrole derivatives of formula (I) and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
Public/Granted literature
- US20050107370A1 Pyrrole derivatives as antimycobacterial compounds Public/Granted day:2005-05-19
Information query
IPC分类: