Invention Grant
US07691846B2 Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
有权
含有内酰胺的化合物及其衍生物作为因子Xa抑制剂
- Patent Title: Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
- Patent Title (中): 含有内酰胺的化合物及其衍生物作为因子Xa抑制剂
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Application No.: US12401401Application Date: 2009-03-10
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Publication No.: US07691846B2Publication Date: 2010-04-06
- Inventor: Donald J. P. Pinto
- Applicant: Donald J. P. Pinto
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Main IPC: C07D519/00
- IPC: C07D519/00 ; A61K31/55 ; A61K31/445 ; A61P7/02
Abstract:
The present application describes lactam-containing compounds and derivatives thereof of Formula I: P4-P-M-M4 I or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
Public/Granted literature
- US20090176758A1 LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS Public/Granted day:2009-07-09
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