Invention Grant
- Patent Title: Metalloprotease inhibitors containing a heterocyclic moiety
- Patent Title (中): 含有杂环部分的金属蛋白酶抑制剂
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Application No.: US12074994Application Date: 2008-03-07
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Publication No.: US07691851B2Publication Date: 2010-04-06
- Inventor: Christian Gege , Arthur Taveras
- Applicant: Christian Gege , Arthur Taveras
- Applicant Address: US CA Thousand Oaks
- Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Elsa D. Lemoine
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61K31/5383
Abstract:
The present invention relates generally to pharmaceutical agents containing a heterocyclic moiety, and in particular, to heterocyclic metalloprotease inhibiting compounds. More particularly, the present invention provides a new class of heterocyclic MMP-13 inhibiting compounds with a modified benzoxazine moiety, that exhibit an increased potency and selectivity in relation to currently known MMP-13 inhibitors.
Public/Granted literature
- US20080221091A1 Metalloprotease inhibitors containing a heterocyclic moiety Public/Granted day:2008-09-11
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