Invention Grant
- Patent Title: Pyrazolopyridines and methods of making and using the same
- Patent Title (中): 吡唑并吡啶及其制备和使用方法
-
Application No.: US10526839Application Date: 2003-09-05
-
Publication No.: US07691865B2Publication Date: 2010-04-06
- Inventor: Wen-Cherng Lee , Mary Beth Carter , Lihong Sun , Paul Lyne , Claudio Chuaqui , Zhongli Zheng , Juswinder Singh , Paula Boriack-Sjodin
- Applicant: Wen-Cherng Lee , Mary Beth Carter , Lihong Sun , Paul Lyne , Claudio Chuaqui , Zhongli Zheng , Juswinder Singh , Paula Boriack-Sjodin
- Applicant Address: US MA Cambridge
- Assignee: Biogen Idec MA Inc.
- Current Assignee: Biogen Idec MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Honigman, Miller, Schwartz & Cohn LLP
- Agent Thomas A. Wootton; Jonathan P. O'Brien
- International Application: PCT/US03/27722 WO 20030905
- International Announcement: WO2004/022054 WO 20040318
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D471/02 ; C07D487/04

Abstract:
Compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I:
Public/Granted literature
- US20060106033A1 Pyrazolopyridines and methods of making and using the same Public/Granted day:2006-05-18
Information query
IPC分类: