Invention Grant
- Patent Title: Methods and composition based on discovery of metabolism of nitroglycerin
- Patent Title (中): 基于硝酸甘油代谢发现的方法和组成
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Application No.: US10508957Application Date: 2003-02-24
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Publication No.: US07691907B2Publication Date: 2010-04-06
- Inventor: Jonathan S. Stamler , Zhiqiang Chen
- Applicant: Jonathan S. Stamler , Zhiqiang Chen
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Bacon & Thomas
- International Application: PCT/US03/03126 WO 20030224
- International Announcement: WO03/075832 WO 20030918
- Main IPC: A61K31/095
- IPC: A61K31/095 ; A61K31/045
Abstract:
Therapies are for treating patients in need of nitroglycerin therapy and allow increased dosage, postponement of tolerance and preconditioning, without exacerbating or causing hypotension. Methods for determining cross-tolerance, nitroglycerin effectiveness and dose are also disclosed. Composition for intravenous administration of nitroglycerin does not contain ethanol or contains less ethanol than conventional compositions.
Public/Granted literature
- US20050131063A1 Methods and composition based on discovery of metabolism of nitroglycerin Public/Granted day:2005-06-16
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