Invention Grant
US07691970B2 Muteins of a bilin-binding protein with affinity for a given target
有权
胆固醇结合蛋白的突变蛋白与给定靶标具有亲和性
- Patent Title: Muteins of a bilin-binding protein with affinity for a given target
- Patent Title (中): 胆固醇结合蛋白的突变蛋白与给定靶标具有亲和性
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Application No.: US10569133Application Date: 2003-08-25
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Publication No.: US07691970B2Publication Date: 2010-04-06
- Inventor: Arne Skerra , Steffen Schlehuber
- Applicant: Arne Skerra , Steffen Schlehuber
- Applicant Address: DE Freising-Weihenstephan
- Assignee: Pieris AG
- Current Assignee: Pieris AG
- Current Assignee Address: DE Freising-Weihenstephan
- Agency: Foley & Lardner LLP
- International Application: PCT/EP03/09403 WO 20030825
- International Announcement: WO2005/019254 WO 20050303
- Main IPC: C07K14/00
- IPC: C07K14/00
Abstract:
The present invention relates to novel muteins derived from a bilin-binding protein (BBP) that binds a given target, for example a macromolecular target, with detectable affinity. In particular, the invention relates to a mutein of the bilin-binding protein of Pieris brassicae. The invention also refers to a corresponding nucleic acid molecule encoding such a mutein and to a method for its generation. The invention further refers to a method for producing such a mutein. Finally, the invention is directed to a pharmaceutical composition comprising such a lipocalin mutein as well as to various use of the mutein.
Public/Granted literature
- US20070148201A1 Muteins of a bilin-binding protein with affinity for a given target Public/Granted day:2007-06-28
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