Invention Grant
- Patent Title: Chimera botulinum toxin type E
- Patent Title (中): 嵌合体肉毒毒素E型
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Application No.: US11036532Application Date: 2005-01-14
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Publication No.: US07691983B2Publication Date: 2010-04-06
- Inventor: Ester Fernandez-Salas , Lance E. Steward , Todd Herrington , K. Roger Aoki
- Applicant: Ester Fernandez-Salas , Lance E. Steward , Todd Herrington , K. Roger Aoki
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agency: Allergan, Inc.
- Agent Dean G. Stathakis; Joel B. German
- Main IPC: C07K14/33
- IPC: C07K14/33
Abstract:
The present invention relates to a toxin comprising a modified light chain of a botulinum toxin type E, wherein the modified light chain comprises amino acid sequence PFVNKQFN (SEQ ID NO: 120) at the N-terminus, and amino acid sequence xExxxLL (SEQ ID NO: 112) at the C-terminus, wherein x is any amino acid.
Public/Granted literature
- US20060039929A1 Chimera botulinum toxin type E Public/Granted day:2006-02-23
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