Invention Grant
- Patent Title: siRNA targeting nucleoporin 62kDa (Nup62)
- Patent Title (中): 靶向核蛋白62kDa的siRNA（Nup62）
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Application No.: US12157289Application Date: 2008-06-09
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Publication No.: US07691998B2Publication Date: 2010-04-06
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Kalow & Springut, LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A61K48/00
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for Nup62.
Public/Granted literature
- US20090118489A1 siRNA targeting nucleoporin 62kDa (Nup62) Public/Granted day:2009-05-07
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