Invention Grant
- Patent Title: Methods for the stereoselective synthesis of substituted piperidines
- Patent Title (中): 立体选择性合成取代的哌啶的方法
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Application No.: US11364506Application Date: 2006-02-28
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Publication No.: US07692019B2Publication Date: 2010-04-06
- Inventor: Brian M. Aquila , Thomas D. Bannister , Gregory D. Cuny , James R. Hauske , Michele L. R. Heffernan , Michael Z. Hoemann , Donald W. Kessler , Liming Shao , Xinhe Wu , Roger L. Xie
- Applicant: Brian M. Aquila , Thomas D. Bannister , Gregory D. Cuny , James R. Hauske , Michele L. R. Heffernan , Michael Z. Hoemann , Donald W. Kessler , Liming Shao , Xinhe Wu , Roger L. Xie
- Applicant Address: US MA Marlborough
- Assignee: Sepracor Inc.
- Current Assignee: Sepracor Inc.
- Current Assignee Address: US MA Marlborough
- Agency: Jones Day
- Main IPC: C07D223/04
- IPC: C07D223/04 ; C07D211/60 ; C07D207/46
Abstract:
One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.
Public/Granted literature
- US20060211864A1 Methods for the stereoselective synthesis of substituted piperidines Public/Granted day:2006-09-21
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