Systems and methodologies for integration of an anti virus AV Plug In(s) as part of an Item Store. The semantics for operation of the AV Plug In(s) are provided by the relational Item Store, via employing a metadata component and a scanning component associated with the Item Store. The metadata component can supply a signature value being associated with the Item Store that can represent the time of scanning of data, and outcome for every scanned item. The scanning component can provide for a queuing of items in the data store in a synchronous and/or asynchronous mode for both scanning and cleaning by the AV Plug In supplied by vendors.