Invention Grant
US07695916B2 Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
有权
与冠状动脉事件和药物反应相关的遗传多态性，检测方法及其用途
- Patent Title: Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
- Patent Title (中): 与冠状动脉事件和药物反应相关的遗传多态性，检测方法及其用途
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Application No.: US12077935Application Date: 2008-03-21
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Publication No.: US07695916B2Publication Date: 2010-04-13
- Inventor: Olga Iakoubova , James Devlin , Charles Rowland , Carmen Tong
- Applicant: Olga Iakoubova , James Devlin , Charles Rowland , Carmen Tong
- Applicant Address: US CA Alameda
- Assignee: Celera Corporation
- Current Assignee: Celera Corporation
- Current Assignee Address: US CA Alameda
- Agency: Celera Corporation
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
The present invention provides compositions and methods based on genetic polymorphisms that are associated with coronary heart disease (particularly myocardial infarction), aneurysm/dissection, and/or response to drug treatment, particularly statin treatment. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
Public/Granted literature
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