Invention Grant
US07695923B2 CFTR polypeptides methods to overcome biosynthetic misprocessing
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CFTR多肽的方法来克服生物合成的错误处理
- Patent Title: CFTR polypeptides methods to overcome biosynthetic misprocessing
- Patent Title (中): CFTR多肽的方法来克服生物合成的错误处理
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Application No.: US11565551Application Date: 2006-11-30
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Publication No.: US07695923B2Publication Date: 2010-04-13
- Inventor: John R. Riordan , Xiu-Bao Chang
- Applicant: John R. Riordan , Xiu-Bao Chang
- Applicant Address: US MN Rochester
- Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee: Mayo Foundation for Medical Education and Research
- Current Assignee Address: US MN Rochester
- Agency: Fish & Richardson P.C.
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The invention relates to biosynthetic maturation of cell surface polypeptides and, more specifically, to particular CFTR polypeptides which exhibit increased transport to the cell surface and tripeptide amino acid sequences that promote or enhance transport of export-incompetent CFTR to the cell surface.
Public/Granted literature
- US20080020418A1 CFTR POLYPEPTIDES, FRAGMENTS THEREOF AND METHODS OF USE TO OVERCOME BIOSYNTHETIC MISPROCESSING Public/Granted day:2008-01-24
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