Invention Grant
- Patent Title: Method for the cultivation of primary cells and for the amplification of viruses under serum free conditions
- Patent Title (中): 在无血清条件下培养原代细胞和扩增病毒的方法
-
Application No.: US11071814Application Date: 2005-03-03
-
Publication No.: US07695939B2Publication Date: 2010-04-13
- Inventor: Ingmar Rathe , Eva Felder , Karl Heller
- Applicant: Ingmar Rathe , Eva Felder , Karl Heller
- Applicant Address: DK Kvistgaard
- Assignee: Bavarian Nordic A/S
- Current Assignee: Bavarian Nordic A/S
- Current Assignee Address: DK Kvistgaard
- Agency: Law Office of Salvatore Arrigo
- Priority: DK200201302 20020905
- Main IPC: A61K39/38
- IPC: A61K39/38 ; A61K39/275 ; C12P21/04 ; C12N15/64 ; C12N7/00 ; C12N5/00 ; A61K39/155
Abstract:
The present invention relates to a method for the cultivation of primary cells. The primary cells are cultivated in a serum free medium comprising a factor selected from the group consisting of growth factors and attachment factors. The method for the cultivation of primary cells may be one step in a method for the amplification of viruses, such as poxviruses. According to this latter method the primary cells are cultivated in a serum free medium comprising a factor selected from the group consisting of growth factors and attachment factors. The cells are then infected with the virus and the infected cells are cultivated in serum free medium until progeny virus is produced.
Public/Granted literature
Information query
