Invention Grant
US07696130B2 PNA chip using plastic substrate coated with epoxy group-containing polymer, method of manufacturing the PNA chip, and method of detecting single nucleotide polymorphism using the PNA chip
失效
使用涂有含环氧基聚合物的塑料基材的PNA芯片，PNA芯片的制造方法以及使用PNA芯片检测单核苷酸多态性的方法
- Patent Title: PNA chip using plastic substrate coated with epoxy group-containing polymer, method of manufacturing the PNA chip, and method of detecting single nucleotide polymorphism using the PNA chip
- Patent Title (中): 使用涂有含环氧基聚合物的塑料基材的PNA芯片，PNA芯片的制造方法以及使用PNA芯片检测单核苷酸多态性的方法
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Application No.: US11156653Application Date: 2005-06-21
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Publication No.: US07696130B2Publication Date: 2010-04-13
- Inventor: Jeongmin Ha , Jae Young Jang , In Soo Kim
- Applicant: Jeongmin Ha , Jae Young Jang , In Soo Kim
- Applicant Address: KR Seoul
- Assignee: LG Life Sciences, Ltd.
- Current Assignee: LG Life Sciences, Ltd.
- Current Assignee Address: KR Seoul
- Agency: McKenna Long & Aldridge LLP
- Priority: KR10-2004-0047677 20040624
- Main IPC: C40B50/18
- IPC: C40B50/18
Abstract:
Provided is a PNA (Peptide Nucleic Acid) chip in which a probe PNA containing a desired DNA sequence is immobilized on a plastic substrate coated with an epoxy group-containing polymer. Therefore, single-stranded PNAs can be immobilized on a transparent plastic substrate by means of an epoxy group-containing polymer layer in an efficient and cost-effective manner. Fluorescence signal detection based on PNA/DNA hybridization enables identification of SNP (Single Nucleotide Polymorphism).
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