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US07696150B2 Modulation of the activity of an interleukin 17 receptor-related protein, EVI27, and uses thereof 有权
调节白细胞介素17受体相关蛋白,EVI27的活性及其用途

Modulation of the activity of an interleukin 17 receptor-related protein, EVI27, and uses thereof
Abstract:
The present invention describes the cloning and molecular and cellular characterization of a novel protein with homology to the IL-17 receptor. The gene was cloned by virtue of its proximity to a common site of retroviral integration in a murine acute myeloid leukemia. The gene described herein possibly codes for a novel interleukin receptor that binds an as yet unidentified cytokine ligand, and may be useful in cancer diagnostics and therapies that rely on immune system modulation.
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