Invention Grant
US07696151B2 Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
失效
使用硬脂酰CoA去饱和酶鉴定甘油三酯还原治疗剂的方法和组合物
- Patent Title: Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
- Patent Title (中): 使用硬脂酰CoA去饱和酶鉴定甘油三酯还原治疗剂的方法和组合物
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Application No.: US11178808Application Date: 2005-07-11
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Publication No.: US07696151B2Publication Date: 2010-04-13
- Inventor: Michael R. Hayden , Alison J. Brownlie , James M. Ntambi , Makoto Miyazaki , Mark P. Gray-Keller , Alan D. Attie
- Applicant: Michael R. Hayden , Alison J. Brownlie , James M. Ntambi , Makoto Miyazaki , Mark P. Gray-Keller , Alan D. Attie
- Applicant Address: CA Burnaby US WI Madison
- Assignee: Xenon Pharmaceuticals Inc.,Wisconsin Alumni Research Foundation
- Current Assignee: Xenon Pharmaceuticals Inc.,Wisconsin Alumni Research Foundation
- Current Assignee Address: CA Burnaby US WI Madison
- Agent Elliot M. Olstein; Alan J. Grant
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K38/00 ; A61K31/20
Abstract:
The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL, total cholesterol, or production of secretions from mucous membranes, monounsaturated fatty acids, wax esters, and the like, is disclosed. Also disclosed are conventions useful in the prevention and/or treatment of such diseases.
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