Invention Grant
US07696154B2 Methods for treating interleukin-18 mediated disorders with interleukin-18 binding proteins
有权
用白细胞介素-18结合蛋白治疗白细胞介素-18介导的病症的方法
- Patent Title: Methods for treating interleukin-18 mediated disorders with interleukin-18 binding proteins
- Patent Title (中): 用白细胞介素-18结合蛋白治疗白细胞介素-18介导的病症的方法
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Application No.: US11724737Application Date: 2007-03-15
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Publication No.: US07696154B2Publication Date: 2010-04-13
- Inventor: Daniela Novick , Charles Dinarello , Menachem Rubinstein , Soo Hyun Kim , Yolande Chvatchko , Christine Plater-Zyberk
- Applicant: Daniela Novick , Charles Dinarello , Menachem Rubinstein , Soo Hyun Kim , Yolande Chvatchko , Christine Plater-Zyberk
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Company Ltd.
- Current Assignee: Yeda Research and Development Company Ltd.
- Current Assignee Address: IL Rehovot
- Agency: Mintz Levin, Cohn, Ferris, Glovsky and Popeo P.C.
- Agent Ivor R. Elrifi; Cynthia Kozakiewicz
- Priority: IL121554 19970814; IL121639 19970827; IL121860 19970929; IL122134 19971106; IL125463 19980722; EP00103590 20000221; EP00103597 20000221; EP00125633 20001123
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
Interleukin-18 binding proteins which are capable of binding IL-18 and of modulating and/or blocking IL-18 activity are provided. Methods for the isolation and recombinant production, DNAs encoding them. DNA vectors expressing them, vectors useful for their expression in humans and other mammals, antibodies against them are also provided. Therapeutic uses of IL-18 binding proteins and further inhibitors of IL-18 are also provided according to the invention.
Public/Granted literature
- US20070173439A1 Interleukin-18 binding proteins, their preparation and use Public/Granted day:2007-07-26
Information query
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