Invention Grant
- Patent Title: Crystalline compound
- Patent Title (中): 结晶化合物
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Application No.: US11962838Application Date: 2007-12-21
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Publication No.: US07696191B2Publication Date: 2010-04-13
- Inventor: James McCabe , Gary Peter Tomkinson
- Applicant: James McCabe , Gary Peter Tomkinson
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: A01N43/00
- IPC: A01N43/00 ; A61K31/397 ; A61K31/00 ; A01N43/58 ; A61K31/50 ; A01N43/60 ; A61K31/495 ; A61K31/497 ; A01N43/56

Abstract:
A novel crystalline form of 3-{[5-(azetidin-1-ylcarbonyl)pyrazin-2-yl]oxy}-5-[(1-methylethyl)oxy]-N-1H-pyrazol-3-ylbenzamide is described in the specification. This compound is a glucokinase (GLK or GK) activator and useful as a pharmaceutical agent in the treatment or prevention of a disease or medical condition mediated through GLK, leading to a decreased glucose threshold for insulin secretion. Processes for the manufacture of the crystalline form, pharmaceutical compositions comprising the crystalline form and the use of the crystalline form in medical treatment are also described.
Public/Granted literature
- US20080153800A1 NOVEL CRYSTALLINE COMPOUND Public/Granted day:2008-06-26
Information query
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