Invention Grant
- Patent Title: DNA-PK inhibitors
- Patent Title (中): DNA-PK抑制剂
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Application No.: US11403606Application Date: 2006-04-13
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Publication No.: US07696203B2Publication Date: 2010-04-13
- Inventor: Graeme Cameron Murray Smith , Niall Morrison Barr Martin , Keith Allan Menear , Marc Geoffrey Hummersone , Xiao-ling Cockcroft , Mark Frigerio , Roger John Griffin , Bernard Thomas Golding , Ian Robert Hardcastle , David Richard Newell , Hilary Alan Calvert , Nicola Jane Curtin , Kappusamy Saravanan , Marine Desage-El Murr
- Applicant: Graeme Cameron Murray Smith , Niall Morrison Barr Martin , Keith Allan Menear , Marc Geoffrey Hummersone , Xiao-ling Cockcroft , Mark Frigerio , Roger John Griffin , Bernard Thomas Golding , Ian Robert Hardcastle , David Richard Newell , Hilary Alan Calvert , Nicola Jane Curtin , Kappusamy Saravanan , Marine Desage-El Murr
- Applicant Address: GB Cambridge GB London
- Assignee: Kudos Pharmaceuticals Limited,Cancer Research Technology Limited
- Current Assignee: Kudos Pharmaceuticals Limited,Cancer Research Technology Limited
- Current Assignee Address: GB Cambridge GB London
- Agency: Michael Best & Friedrich LLP
- Priority: GB0507831.6 20050418
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14
Abstract:
Compounds of formula I: wherein A, B and D are respectively selected from the group consisting of: (i) CH, NH, C; (ii) CH, N, N; and (iii) CH, O, C; the dotted lines represent two double bonds in the appropriate locations; and where Z is selected from S, O, C(═O), CH2 and NH are disclosed for use in inhibiting DNA-PK.
Public/Granted literature
- US20060264427A1 DNA-PK inhibitors Public/Granted day:2006-11-23
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