Invention Grant
- Patent Title: Pharmaceutical compounds
- Patent Title (中): 药物化合物
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Application No.: US12089677Application Date: 2006-10-11
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Publication No.: US07696204B2Publication Date: 2010-04-13
- Inventor: Edward McDonald , Jonathan M Large , Stephen J Shuttleworth
- Applicant: Edward McDonald , Jonathan M Large , Stephen J Shuttleworth
- Applicant Address: CH Zurich GB London GB London JP Tokyo CH Basel
- Assignee: Ludwig Institute for Cancer Research,Cancer Research Technology Limited,The Institute of Cancer Research: Royal Cancer Hospital,Astellas Pharma, Inc.,F. Hoffmann-La Roche AG
- Current Assignee: Ludwig Institute for Cancer Research,Cancer Research Technology Limited,The Institute of Cancer Research: Royal Cancer Hospital,Astellas Pharma, Inc.,F. Hoffmann-La Roche AG
- Current Assignee Address: CH Zurich GB London GB London JP Tokyo CH Basel
- Agency: Nixon & Vanderhye P.C.
- Priority: GB0520657.8 20051011
- International Application: PCT/GB2006/003782 WO 20061011
- International Announcement: WO2007/042810 WO 20070419
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K31/505
Abstract:
Pyrimidines of formula (I): wherein R1 to R4, X and Y are defined in the specification are inhibitors of P13K and may thus be used to treat diseases and disorders arising from abnormal cell growth, function or behavior associated with P13 kinase such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.
Public/Granted literature
- US20090042884A1 Pharmaceutical Compounds Public/Granted day:2009-02-12
Information query
