Invention Grant
US07696212B2 Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
有权
黄嘌呤衍生物，其制备及其作为药物组合物的用途
- Patent Title: Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
- Patent Title (中): 黄嘌呤衍生物，其制备及其作为药物组合物的用途
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Application No.: US12331720Application Date: 2008-12-10
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Publication No.: US07696212B2Publication Date: 2010-04-13
- Inventor: Frank Himmelsbach , Elke Langkopf , Matthias Eckhardt , Roland Maier , Ralf Lotz , Michael Mark , Mohammad Tadayyon
- Applicant: Frank Himmelsbach , Elke Langkopf , Matthias Eckhardt , Roland Maier , Ralf Lotz , Michael Mark , Mohammad Tadayyon
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim Pharma GmbH and Co. KG
- Current Assignee: Boehringer Ingelheim Pharma GmbH and Co. KG
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Mary-Ellen M. Devlin; David L. Kershner
- Priority: DE10251927 20021108
- Main IPC: C07D473/06
- IPC: C07D473/06 ; C07D519/00 ; A61K31/522 ; A61K31/538 ; A61K31/536 ; A61K31/5415 ; A61K31/5513 ; A61P3/10 ; A61P3/04
Abstract:
Disclosed are substituted xanthines of general formula wherein R1 to R4 are defined hereinbelow, the tautomers, the stereoisomers, the mixtures thereof, the prodrugs thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibitory effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
Public/Granted literature
- US20090093457A1 XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS Public/Granted day:2009-04-09
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