Invention Grant
US07696215B2 4-oxoquinazolin-3-yl benzamide derivatives for the treatment of cytokine diseases
失效
4-氧代喹唑啉-3-基苯甲酰胺衍生物，用于治疗细胞因子疾病
- Patent Title: 4-oxoquinazolin-3-yl benzamide derivatives for the treatment of cytokine diseases
- Patent Title (中): 4-氧代喹唑啉-3-基苯甲酰胺衍生物，用于治疗细胞因子疾病
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Application No.: US11817137Application Date: 2006-02-23
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Publication No.: US07696215B2Publication Date: 2010-04-13
- Inventor: Ian Alun Nash , Jonathan Erle Finlayson , Caroline Rachel Thompson
- Applicant: Ian Alun Nash , Jonathan Erle Finlayson , Caroline Rachel Thompson
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Priority: GB0504019.1 20050226
- International Application: PCT/GB2006/000618 WO 20060223
- International Announcement: WO2006/090143 WO 20060831
- Main IPC: A61K31/517
- IPC: A61K31/517
Abstract:
The invention concerns a compound of the Formula (I) wherein m is 1-2 and each R1 is a group such as cyano, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy; R2 is trifluoromethyl or (1-6C)alkyl; R3 is hydrogen or halogeno; and R4 is isoxazolyl; or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Public/Granted literature
- US20090124604A1 4-OXOQUINAZOLIN-3-YL BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CYTOKINE DISEASES Public/Granted day:2009-05-14
Information query
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