Invention Grant
- Patent Title: Humanized antibodies
- Patent Title (中): 人源化抗体
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Application No.: US11519322Application Date: 2006-09-11
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Publication No.: US07696324B2Publication Date: 2010-04-13
- Inventor: Fang Fang , Lori Kohlstaedt , John Reno
- Applicant: Fang Fang , Lori Kohlstaedt , John Reno
- Applicant Address: US CA San Diego
- Assignee: Perlan Therapeutics, Inc.
- Current Assignee: Perlan Therapeutics, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Foley & Lardner, LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C12P21/08
Abstract:
Humanized antibodies that bind ICAM-1 are provided. Antibodies include those selected from: SEQ ID NO:1 and 3 (HumA); SEQ ID NO:5 and 7 (HumB); SEQ ID NO:9 and 11 (HumC); SEQ ID NO:13 and 15 (HumD); SEQ ID NO:17 and 19 (HumE); SEQ ID NO:21 and 23 (HumF); SEQ ID NO:25 and 27 (HumG); SEQ ID NO:29 and 31 (HumH); and SEQ ID NO:33 and 35 (HumI). Subsequences of the humanized antibodies capable of binding an ICAM-1 epitope are also provided. Methods of inhibiting pathogen infection (e.g., HRV) of a cell employing humanized antibodies capable of binding an ICAM-1 epitope are further provided.
Public/Granted literature
- US20070071742A1 Humanized antibodies Public/Granted day:2007-03-29
Information query
