Provided is a method and an apparatus for driving a display panel with a temperature compensated driving voltage, which comprises a temperature sensor, a temperature section register, a comparing unit, a voltage register, a voltage controller and a driver. The comparing unit compares temperature data output from the temperature sensor to temperature section data stored in the temperature section register and outputs comparison data having predetermined bits. The voltage controller selects voltage data corresponding to the comparison data from the voltage data stored in the voltage register and outputs a voltage control signal corresponding to the selected voltage data. The driver outputs a driving voltage corresponding to the voltage control signal to the display panel from among the different driving voltages.