A method and apparatus for scanning exclusively locked files uses a kernel mode driver to scan the operating system's table of applications and identify a handle that owns an exclusive lock for an exclusively locked file. In one embodiment, the kernel mode driver then copies the handle and passes the handle over to a handle list of the anti-virus application requesting access to the exclusively locked file and provides the anti-virus application with the access handle reference number. Armed with the access handle reference number for the copied handle, the anti-virus application can then open the exclusively locked file and scan the exclusively locked file as it would any other file.