Invention Grant
- Patent Title: Method for introducing an ultraviolet light activated viral vector into the spinal column
- Patent Title (中): 将紫外光活化的病毒载体导入脊柱的方法
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Application No.: US10357273Application Date: 2003-01-31
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Publication No.: US07704272B2Publication Date: 2010-04-27
- Inventor: Paul T. Rubery , Edward M. Schwarz
- Applicant: Paul T. Rubery , Edward M. Schwarz
- Applicant Address: US NY Rochester
- Assignee: University of Rochester
- Current Assignee: University of Rochester
- Current Assignee Address: US NY Rochester
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: A61N5/06
- IPC: A61N5/06 ; A01N63/00
Abstract:
In accordance with the present invention, methods and structures are provided for the treatment of functional spinal unit injuries through the use of light activated gene therapy to induce bone fusion through the introduction of a desired gene into a patient's spinal tissue. Methods and structures are also provided for the utilization of ultraviolet light activated gene therapy to repair/rebuild an injured intervertebral disc through the introduction of a desired gene into a patient's spinal tissue. An implant system including a light probe and an implant with which r-AAV is integrated is also provided.
Public/Granted literature
- US20040049249A1 Light activated gene transduction for cell targeted gene delivery in the spinal column Public/Granted day:2004-03-11
Information query
