Invention Grant
- Patent Title: In vivo production of a clostridial neurotoxin light chain peptide
- Patent Title (中): 梭菌神经毒素轻链肽的体内产生
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Application No.: US10854726Application Date: 2004-05-27
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Publication No.: US07704685B2Publication Date: 2010-04-27
- Inventor: Nicholas M. Boulis
- Applicant: Nicholas M. Boulis
- Applicant Address: US OH Cleveland
- Assignee: The Cleveland Clinic Foundation
- Current Assignee: The Cleveland Clinic Foundation
- Current Assignee Address: US OH Cleveland
- Agency: Kenyon & Kenyon LLP
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C07H21/02 ; C07H21/04
Abstract:
A method of producing in a cell in vivo a clostridial neurotoxin light chain peptide by delivering into the cell in vivo a nucleic acid construct. The nucleic acid construct comprises (a) a nucleic acid encoding a clostridial neurotoxin light chain peptide and (b) a regulatory sequence operably linked to the nucleic acid to allow expression of the nucleic acid. The expression of the nucleic acid produces the clostridial neurotoxin light chain peptide in the cell in vivo.
Public/Granted literature
- US20050019346A1 In vivo production of a clostridial neurotoxin light chain peptide Public/Granted day:2005-01-27
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