Invention Grant
- Patent Title: Solid oral dosage form containing an enhancer
- Patent Title (中): 含有增强剂的固体口服剂型
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Application No.: US11733007Application Date: 2007-04-09
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Publication No.: US07704977B2Publication Date: 2010-04-27
- Inventor: Thomas W. I. Leonard
- Applicant: Thomas W. I. Leonard
- Applicant Address: IE Dublin
- Assignee: Merrion Research III Limited
- Current Assignee: Merrion Research III Limited
- Current Assignee Address: IE Dublin
- Agency: Myers Bigel Sibley & Sajovec P.A.
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A61K31/663 ; A61K31/20 ; A61K9/48
Abstract:
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
Public/Granted literature
- US20070238707A1 Solid Oral Dosage Form Containing an Enhancer Public/Granted day:2007-10-11
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