Invention Grant
- Patent Title: Compounds and compositions useful as cathepsin S inhibitors
- Patent Title (中): 可用作组织蛋白酶S抑制剂的化合物和组合物
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Application No.: US11573451Application Date: 2005-08-16
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Publication No.: US07704996B2Publication Date: 2010-04-27
- Inventor: Terance William Hart , Allan Hallett , Fumiaki Yokokawa , Hajime Hirao , Takeru Ehara , Atsuko Iwasaki , Junichi Sakaki , Keiichi Masuya , Masashi Kishida , Osamu Irie
- Applicant: Terance William Hart , Allan Hallett , Fumiaki Yokokawa , Hajime Hirao , Takeru Ehara , Atsuko Iwasaki , Junichi Sakaki , Keiichi Masuya , Masashi Kishida , Osamu Irie
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Fanelli Strain & Haag PLLC
- Agent Paul D. Strain, Esq.
- Priority: GB0418353.9 20040817
- International Application: PCT/EP2005/008896 WO 20050816
- International Announcement: WO2006/018284 WO 20060223
- Main IPC: C07D239/42
- IPC: C07D239/42 ; A61K31/506
Abstract:
The present invention relates to the use of a 2-cyanopyrimidine compound of the formula wherein R1, R2, R3 and X are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in tautomeric form, as an inhibitor of the activity of cathepsin S.
Public/Granted literature
- US20090048230A1 COMPOUNDS AND COMPOSITIONS USEFUL AS CATHEPSIN S INHIBITORS Public/Granted day:2009-02-19
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