Invention Grant
US07704998B2 Sulfonyl-derivatives as novel inhibitors or histone deacetylase
有权
磺酰衍生物作为新型抑制剂或组蛋白脱乙酰酶
- Patent Title: Sulfonyl-derivatives as novel inhibitors or histone deacetylase
- Patent Title (中): 磺酰衍生物作为新型抑制剂或组蛋白脱乙酰酶
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Application No.: US11926759Application Date: 2007-10-29
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Publication No.: US07704998B2Publication Date: 2010-04-27
- Inventor: Kristof Van Emelen , Janine Arts , Leo-Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noelle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant: Kristof Van Emelen , Janine Arts , Leo-Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noelle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE
- Agent Andrea Jo Kamage
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/495 ; C07D241/04 ; C07D403/04 ; C07D413/14
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20080108601A1 Sulfonyl-Derivatives as Novel Inhibitors or Histone Deacetylase Public/Granted day:2008-05-08
Information query
