Invention Grant
- Patent Title: Inhibitors of AKT activity
- Patent Title (中): AKT活性抑制剂
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Application No.: US11918386Application Date: 2006-04-10
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Publication No.: US07705014B2Publication Date: 2010-04-27
- Inventor: Chixu Chen , Brian W. Eastman , Essa H. Hu
- Applicant: Chixu Chen , Brian W. Eastman , Essa H. Hu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Matthew A. Leff; David A. Muthard
- International Application: PCT/US2006/013280 WO 20060410
- International Announcement: WO2006/110638 WO 20061019
- Main IPC: C07D513/02
- IPC: C07D513/02 ; C07D515/02 ; A01N43/42 ; A61K31/44
Abstract:
The instant invention provides for compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
Public/Granted literature
- US20090062327A1 Inhibitors of AKT Activity Public/Granted day:2009-03-05
Information query
