Invention Grant
US07705030B2 Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation
失效
氨基-5-（5元）杂芳基咪唑酮化合物及其用于分泌酶调节的用途
- Patent Title: Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation
- Patent Title (中): 氨基-5-（5元）杂芳基咪唑酮化合物及其用于分泌酶调节的用途
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Application No.: US12180795Application Date: 2008-07-28
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Publication No.: US07705030B2Publication Date: 2010-04-27
- Inventor: Michael Sotirios Malamas , Ping Zhou , William Floyd Fobare , William Ronald Solvibile , Iwan Suwandi Gunawan , James Joseph Erdei , Yinfa Yan , Patrick Michael Andrae , Dominick Anthony Quagliato
- Applicant: Michael Sotirios Malamas , Ping Zhou , William Floyd Fobare , William Ronald Solvibile , Iwan Suwandi Gunawan , James Joseph Erdei , Yinfa Yan , Patrick Michael Andrae , Dominick Anthony Quagliato
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Ram W. Sabnis
- Main IPC: A61K31/4178
- IPC: A61K31/4178 ; A61K31/4439 ; A61K31/506 ; C07D403/14 ; C07D401/14 ; C07D233/88
Abstract:
The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
Public/Granted literature
- US20080306091A1 AMINO-5-(5-MEMBERED)HETERO-ARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR beta-SECRETASE MODULATION Public/Granted day:2008-12-11
Information query
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