Invention Grant
- Patent Title: Reagents for highly specific detection of peroxynitrite
- Patent Title (中): 高度特异性检测过氧亚硝酸盐的试剂
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Application No.: US11245529Application Date: 2005-10-07
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Publication No.: US07705040B2Publication Date: 2010-04-27
- Inventor: Dan Yang , Hua-Li Wang , Zhen-Ning Sun , Jian-Gang Shen
- Applicant: Dan Yang , Hua-Li Wang , Zhen-Ning Sun , Jian-Gang Shen
- Applicant Address: CN Hong Kong
- Assignee: The University of Hong Kong
- Current Assignee: The University of Hong Kong
- Current Assignee Address: CN Hong Kong
- Agency: Jones Day
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D309/00

Abstract:
This invention provides compositions which specifically reacts with peroxynitrite rather than other reactive oxygen species and reactive nitrogen species. This invention also provides related agents for measuring peroxynitrite. This invention also provides related methods for measuring peroxynitrite in a sample, high-throughput screening fluorescent methods for detecting peroxynitrite and high-throughput methods for screening compounds that increase or decrease the production of peroxynitrite comprising using such compositions and agents.
Public/Granted literature
- US20070082403A1 Reagents for highly specific detection of peroxynitrite Public/Granted day:2007-04-12
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