Invention Grant
US07705133B2 Antibodies which bind variants of the TRP channel family member, LTRPC3
有权
结合TRP通道家族成员LTRPC3的变体的抗体
- Patent Title: Antibodies which bind variants of the TRP channel family member, LTRPC3
- Patent Title (中): 结合TRP通道家族成员LTRPC3的变体的抗体
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Application No.: US12220155Application Date: 2008-07-22
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Publication No.: US07705133B2Publication Date: 2010-04-27
- Inventor: Ning Lee , Jian Chen , Shujian Wu , Michael A. Blanar , Paul C. Levesque , Lucy Sun
- Applicant: Ning Lee , Jian Chen , Shujian Wu , Michael A. Blanar , Paul C. Levesque , Lucy Sun
- Applicant Address: US NJ Preinceton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Preinceton
- Agent Stephen C. D'Amico
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/18 ; A61K39/395
Abstract:
The present invention provides novel polynucleotides encoding LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LTRPC3g, LTRPC3h, LTRPC3i, LTRPC3j, LTRPC3k, or LTRPC3l polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Public/Granted literature
- US20080318257A1 Polynucelotides encoding novel variants of the TRP channel family member, LTRPC3 Public/Granted day:2008-12-25
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