A method of predicting at least one physical change in crack geometry of a crack in a pipeline based on in-line inspection operating pressure is presented. In one method, a first test on a pipeline is performed at a first pressure, which obtains a first set of test data. A second test is performed on the pipeline at a second pressure, obtaining a second set of test data. The first and second sets of test data are compared for any difference. A run comparison software processing device may be employed. In other methods, finite element analysis of crack-like dimensions is performed to predict Crack Mouth Opening Displacement (CMOD) for a given set of crack dimensions for a surface-breaking crack and inline pipe inspection operating run pressure. Another method predicts probability of detection of a crack associated with a given CMOD as a function of pressure in successive inspections.