Invention Grant
US07708994B2 Therapy of autoimmune disease in a patient with an inadequate response to a TNF-α inhibitor 有权
在对TNF-α抑制剂反应不足的患者中自身免疫性疾病的治疗

  • Patent Title: Therapy of autoimmune disease in a patient with an inadequate response to a TNF-α inhibitor
  • Patent Title (中): 在对TNF-α抑制剂反应不足的患者中自身免疫性疾病的治疗
  • Application No.: US11439906
    Application Date: 2006-05-24
  • Publication No.: US07708994B2
    Publication Date: 2010-05-04
  • Inventor: Mark C. Benyunes
  • Applicant: Mark C. Benyunes
  • Applicant Address: US CA South San Francisco
  • Assignee: Genentech, Inc.
  • Current Assignee: Genentech, Inc.
  • Current Assignee Address: US CA South San Francisco
  • Agent Wendy M. Lee
  • Main IPC: A61K39/395
  • IPC: A61K39/395 C07K16/00
Therapy of autoimmune disease in a patient with an inadequate response to a TNF-α inhibitor
Abstract:
The present application describes therapy with antagonists which bind to B cell surface markers, such as CD20. In particular, the application describes the use of such antagonists to treat autoimmune disease in a mammal who experiences an inadequate response to a TNFα-inhibitor.
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