Invention Grant
US07708998B2 Methods of inhibiting unwanted cell proliferation using hedgehog antagonists
有权
使用刺猬蛋白拮抗剂抑制不想要的细胞增殖的方法
- Patent Title: Methods of inhibiting unwanted cell proliferation using hedgehog antagonists
- Patent Title (中): 使用刺猬蛋白拮抗剂抑制不想要的细胞增殖的方法
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Application No.: US10652298Application Date: 2003-08-29
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Publication No.: US07708998B2Publication Date: 2010-05-04
- Inventor: Henryk Dudek , Irina Karavanov , Carmen Pepicelli , Karen Kotkow , Lee L. Rubin
- Applicant: Henryk Dudek , Irina Karavanov , Carmen Pepicelli , Karen Kotkow , Lee L. Rubin
- Applicant Address: US MA Cambridge
- Assignee: Curis, Inc.
- Current Assignee: Curis, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Ropes & Gray LLP
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C12Q1/68 ; G01N33/574
Abstract:
The present application is directed to compositions and methods for inhibiting angiogenesis and treating or preventing unwanted cell proliferation, including tumors, by inhibiting the hedgehog pathway, e.g., with an antagonist of the hedgehog pathway such as those disclosed herein.
Public/Granted literature
- US20040110663A1 Hedgehog antagonists, methods and uses related thereto Public/Granted day:2004-06-10
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