Invention Grant
- Patent Title: Methods for identifying or diagnosing carcinoma cells with metastatic potential based on the measurement of lymphoid genes or their products in carcinoma cells
- Patent Title (中): 基于淋巴样基因或其产物在癌细胞中的测量来鉴定或诊断具有转移潜能的癌细胞的方法
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Application No.: US12218586Application Date: 2008-07-16
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Publication No.: US07709189B1Publication Date: 2010-05-04
- Inventor: Stefan A. Cohen
- Applicant: Stefan A. Cohen
- Agent James C. Simmons
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C12Q1/68 ; G01N33/53
Abstract:
A method of predicting the lymphotrophic metastatic potential of a solid non-lymphoid tumor. The percentage of cells of each of a plurality of representative samples of the tumor which express lymphoid gene products is determined. The metastatic potential is predicted to be low when no tumor cells in all of the samples are detected to express lymphoid gene products. The metastatic potential is predicted to be high when a high percentage of tumor cells in at least one of the samples are detected to express lymphoid gene products. Expression of SYKB in any of a plurality of samples of a primary colon tumor is indicative that the primary colon tumor has lymphotrophic metastatic potential.
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