Invention Grant
- Patent Title: Tumor necrosis factor receptors 6α and 6β
- Patent Title (中): 肿瘤坏死因子受体6α和6＆bgr;
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Application No.: US12463301Application Date: 2009-05-08
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Publication No.: US07709218B2Publication Date: 2010-05-04
- Inventor: Reiner L. Gentz , Reinhard Ebner , Guo-Liang Yu , Steven M. Ruben , Jian Ni , Ping Feng
- Applicant: Reiner L. Gentz , Reinhard Ebner , Guo-Liang Yu , Steven M. Ruben , Jian Ni , Ping Feng
- Applicant Address: US MD Rockville
- Assignee: Human Genome Sciences, Inc.
- Current Assignee: Human Genome Sciences, Inc.
- Current Assignee Address: US MD Rockville
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/563 ; G01N33/577 ; C07K16/00 ; C07K16/18 ; C07K16/28
Abstract:
The present invention relates to novel Tumor Necrosis Factor Receptor proteins. In particular, isolated nucleic acid molecules are provided encoding the human TNFR-6α & -6β proteins. TNFR-6α & -6β polypeptides and antibodies that bind TNFR-6α & -6β polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TNFR-6α & -6β activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
Public/Granted literature
- US20090226456A1 Tumor Necrosis Factor Receptors 6 Alpha & 6 Beta Public/Granted day:2009-09-10
Information query
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