Invention Grant
- Patent Title: Control of function of intracellular Ca ion
- Patent Title (中): 细胞内Ca离子的功能控制
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Application No.: US11811588Application Date: 2007-06-11
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Publication No.: US07709441B2Publication Date: 2010-05-04
- Inventor: Katsuhiko Mikoshiba , Junji Hirota , Hideaki Ando
- Applicant: Katsuhiko Mikoshiba , Junji Hirota , Hideaki Ando
- Applicant Address: JP Saitama
- Assignee: Japan Science and Technology Agency
- Current Assignee: Japan Science and Technology Agency
- Current Assignee Address: JP Saitama
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Peter F. Corless; Christine C. O'Day
- Priority: JP2003-141083 20030519
- Main IPC: A61K8/66
- IPC: A61K8/66 ; A61K38/00

Abstract:
Analysis of substance capable of binding with inositol-1,4,5-triphosphate (IP3) receptor (IP3R), preferably with a regulation domain of IP3R; analysis of the function of IP3R; and establishing of a method of treatment or diagnosis for various malfunctions and diseases associated with IP3R. In particular, control of the activity of intracellular Ca2+ release. More specifically, a regulator for the activity of inositol-1,4,5-triphosphate (IP3) receptor (IP3R), comprised of carbonic anhydrase related protein (CARP); a control agent for intracellular calcium release, comprised of carbonic anhydrase related protein (CARP); and a method of control therewith.
Public/Granted literature
- US20080064082A1 Control of function of intracellular Ca ion Public/Granted day:2008-03-13
Information query