Invention Grant
US07709448B2 Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
有权
5-氨基-3-（3'-脱氧-β-呋喃核糖基） - 噻唑并[4,5-d]嘧啶-2,7-二酮的前药
![Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione](/docs/US/2010-05-04/US07709448B2/abs.jpg.600x600.jpg)
- Patent Title: Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
- Patent Title (中): 5-氨基-3-（3'-脱氧-β-呋喃核糖基） - 噻唑并[4,5-d]嘧啶-2,7-二酮的前药
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Application No.: US11766724Application Date: 2007-06-21
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Publication No.: US07709448B2Publication Date: 2010-05-04
- Inventor: Gregory J. Haley , Joseph R. Lennox , Alan X. Xiang , Stephen E. Webber
- Applicant: Gregory J. Haley , Joseph R. Lennox , Alan X. Xiang , Stephen E. Webber
- Applicant Address: US CA San Diego
- Assignee: Anadys Pharmaceuticals, Inc.
- Current Assignee: Anadys Pharmaceuticals, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Connolly Bove Lodge & Hutz LLP
- Agent Mark J. Pino
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
![Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione](/abs-image/US/2010/05/04/US07709448B2/abs.jpg.150x150.jpg)
Abstract:
The invention is directed to 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione prodrugs, whose metabolized parent compound has immunomodulatory activity. The invention also relates to the therapeutic use of such prodrugs and pharmaceutical compositions thereof in treating disease states associated with abnormal cell growth, such as cancer.
Public/Granted literature
- US20080032999A1 Prodrugs of 5-amino-3-(3'-deoxy-b-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione Public/Granted day:2008-02-07
Information query
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