Invention Grant
- Patent Title: Phosphorous containing compounds including triphenylmethylphosphonate esters for the treatment of melanoma and other cancers
- Patent Title (中): 含磷化合物，包括用于治疗黑素瘤和其他癌症的三苯基甲基膦酸酯
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Application No.: US11750952Application Date: 2007-05-18
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Publication No.: US07709465B2Publication Date: 2010-05-04
- Inventor: Paul J. Hergenrother , Vitaliy Nesterenko , Karson S. Putt , Rahul Palchaudhuri
- Applicant: Paul J. Hergenrother , Vitaliy Nesterenko , Karson S. Putt , Rahul Palchaudhuri
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Greenlee, Winner and Sullivan, P.C.
- Main IPC: A61K31/66
- IPC: A61K31/66 ; C07F9/02
Abstract:
Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. Particularly disclosed are phosphonate esters. Compounds, methods of making the compounds, medicaments and method of manufacture of medicaments and therapeutic methods with applications against cancer including breast cancer, melanoma, colon cancer, leukemia and lymphoma, and other cancer cells are described.
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