Invention Grant
US07709470B2 11-phenyl-dibenzodiazepine derivatives as RXR-antagonists
失效
11-苯基 - 二苯并二氮杂衍生物作为RXR-拮抗剂
- Patent Title: 11-phenyl-dibenzodiazepine derivatives as RXR-antagonists
- Patent Title (中): 11-苯基 - 二苯并二氮杂衍生物作为RXR-拮抗剂
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Application No.: US10550776Application Date: 2004-04-08
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Publication No.: US07709470B2Publication Date: 2010-05-04
- Inventor: Junichi Sakaki , Kazuhide Konishi , Masashi Kishida , Masaaki Kimura , Hidefumi Uchiyama , Hironobu Mitani
- Applicant: Junichi Sakaki , Kazuhide Konishi , Masashi Kishida , Masaaki Kimura , Hidefumi Uchiyama , Hironobu Mitani
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Theresa Devlin
- Priority: GB0308335.9 20030410
- International Application: PCT/EP2004/003806 WO 20040408
- International Announcement: WO2004/089916 WO 20041021
- Main IPC: A61P3/00
- IPC: A61P3/00 ; A61K31/551 ; C07D243/38
Abstract:
The present invention relates to novel benzodiazepine compounds exhibiting RXR-antagonist efficacy, for delaying progression of, preventing or treating a condition or disease being associated with RXR-antagonism, in particular selected from diabetes, complication of diabetes such as retinopathy, nephropathy, neuropathy, and hyperlipidemia, obesity, dyslipidemia, and osteoporosis.
Public/Granted literature
- US20070043029A1 11-Phenyl-dibenzodiazepine derivatives as rxr-antagonists Public/Granted day:2007-02-22
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