Invention Grant
- Patent Title: CXCR4 antagonists
- Patent Title (中): CXCR4拮抗剂
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Application No.: US12182044Application Date: 2008-07-29
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Publication No.: US07709486B2Publication Date: 2010-05-04
- Inventor: Gary J. Bridger , Eva Maria Boehringer , Zhongren Wang , Dominique Schols , Renato Tony Skerlj , David Earl Bogucki
- Applicant: Gary J. Bridger , Eva Maria Boehringer , Zhongren Wang , Dominique Schols , Renato Tony Skerlj , David Earl Bogucki
- Applicant Address: US MA Cambridge
- Assignee: Genzyme Corporation
- Current Assignee: Genzyme Corporation
- Current Assignee Address: US MA Cambridge
- Agency: Morrisson & Foerster LLP
- Main IPC: A61P19/02
- IPC: A61P19/02 ; A61P1/00 ; A61P35/00 ; A61K31/497 ; A61K31/395 ; A61K31/33 ; A61K31/44 ; A61K31/675 ; C07D257/02 ; C07D487/08

Abstract:
The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.
Public/Granted literature
- US20080287454A1 CXCR4 ANTAGONISTS Public/Granted day:2008-11-20
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