Invention Grant
US07709487B2 Sulfonyl-derivatives as novel inhibitors of histone deacetylase
有权
磺酰基衍生物作为组蛋白脱乙酰酶的新型抑制剂
- Patent Title: Sulfonyl-derivatives as novel inhibitors of histone deacetylase
- Patent Title (中): 磺酰基衍生物作为组蛋白脱乙酰酶的新型抑制剂
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Application No.: US11668906Application Date: 2007-01-30
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Publication No.: US07709487B2Publication Date: 2010-05-04
- Inventor: Kristof Van Emelen , Janine Arts , Leo Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noelle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant: Kristof Van Emelen , Janine Arts , Leo Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noelle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D403/04
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20070142393A1 SULFONYL-DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2007-06-21
Information query
IPC分类:
