Invention Grant
US07709502B2 Substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimides and 1-oxoisoindolines
失效
取代的2-(2,6-二氧代哌啶-3-基) - 邻苯二甲酰亚胺和1-氧代异吲哚啉
- Patent Title: Substituted 2-(2,6-dioxopiperidin-3-yl)-phthalimides and 1-oxoisoindolines
- Patent Title (中): 取代的2-(2,6-二氧代哌啶-3-基) - 邻苯二甲酰亚胺和1-氧代异吲哚啉
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Application No.: US11401858Application Date: 2006-04-12
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Publication No.: US07709502B2Publication Date: 2010-05-04
- Inventor: George W. Muller , David I. Stirling , Roger Shen-Chu Chen
- Applicant: George W. Muller , David I. Stirling , Roger Shen-Chu Chen
- Applicant Address: US NJ Summit
- Assignee: Celgene Corporation
- Current Assignee: Celgene Corporation
- Current Assignee Address: US NJ Summit
- Agency: Jones Day
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D401/04

Abstract:
Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines are disclosed. The compounds are useful, for example, in reducing the levels of TNFα in a mammal.
Public/Granted literature
- US20060183910A1 Pharmaceutical compositions of 4-amino-2-(3-methyl-2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione Public/Granted day:2006-08-17
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